Emotional Processing and Brain Metabolism after Pharmacological Stimulation with Ketamine
نویسندگان
چکیده
M. Scheidegger, S. Grimm, A. Fuchs, R. Kraehenmann, H. Boeker, E. Seifritz, P. Boesiger, M. Walter, and A. Henning Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland, Clinic of Affective Disorders and General Psychiatry, Psychiatric University Hospital Zurich, Zurich, Switzerland, Cluster Languages of Emotion, Freie Universität Berlin, Berlin, Germany, Clinical Affective Neuroimaging Laboratory, Psychiatric University Hospital, Magdeburg, Germany
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Ketamine administration reduces limbic reactivity during emotional stimulation – An fMRI study in healthy subjects
INTRODUCTION Previous studies using emotional fMRI paradigms reported enhanced responses in brain structures involved in mood regulation like the amygdala, hippocampus, insula, and orbitofrontal cortex in depressed patients compared with healthy controls (for review see [1]). Many related neuroimaging findings are compatible with the hypothesis that limbic hyperactivity, e.g. in the amygdala, d...
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